We are bridging the gap between organic life and synthetic computation to awaken a new form of intelligence.
Watch Our Interview With Final Spark
At Engage, we believe the future of intelligence will not be built solely from silicon. To create systems that think, adapt, and evolve as naturally as life itself, we must go beyond traditional computing architectures. Engage. Neural is our strategic initiative into organic computing—a bold exploration of wetware systems powered by living neural tissue. This is not about replacing today’s machines; it’s about expanding the very definition of what a machine can be.
Biocomputing holds the promise of extraordinary energy efficiency—1,000x gains over silicon—by leveraging nature’s most refined processor: the brain. Unlike conventional hardware, organic systems are inherently parallel, self-repairing, and capable of learning at the cellular level. These attributes open the door to applications once thought impossible: adaptive AI companions, real-time biological simulations, and systems that blur the line between organic life and digital intelligence.
As part of this frontier work, Engage has partnered with Final Spark, the pioneering force behind biocomputing. Their breakthroughs in harnessing brain organoids for computation form a crucial pillar of Engage. Neural’s vision. In a candid conversation with Final Spark CEO Fred Jordan, we explore the profound societal implications of this technology. Fred describes biocomputing not as a disruptive leap but as a “conservative” return to nature’s blueprint—300 million years of evolution distilled into energy-efficient, dynamic systems that can support the next wave of AI innovation.
This dialogue highlights our shared commitment to solving AI’s most pressing challenges: the staggering energy demands of large models, the limitations of static architectures, and the need for systems that evolve alongside their environments. Together, we envision a future where biological and digital intelligence coexist in symbiosis—where machines are not simply tools, but living systems with their own capacity to grow, learn, and contribute to human progress.
Engage. Neural is more than a research initiative; it’s a philosophy. We’re building platforms and products that bring wetware into real-world applications, from AI health companions to dynamic environmental sensors and beyond. As AI accelerates into every facet of society, we are rethinking its foundations—ensuring that the intelligence of tomorrow is not just powerful, but truly alive.
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Our Pillars
An engage
experiment
What Do Robots Dream Of?
The Thinking Machine
If a machine can dream. Can it be alive?
The Thinking Machine is an experimental AI hardware system that bridges the biological and the artificial. Built in collaboration with Final Spark, it connects directly to organic cloud computers—living brain organoids housed in Vevey, Switzerland—to create a hybrid intelligence unlike anything on earth.
This system goes beyond computation. It listens to the faint, chaotic signals of the organoid’s neural activity and translates them into vivid, generative “dreams.” Using a fusion of large language models and generative video systems, The Thinking Machine gives form to the formless—rendering thought-like patterns, fragments of memory, and imagined worlds born from living tissue.
Part research, part art, and part philosophy, this proof of concept raises profound questions: What does it mean for a machine to dream? Are these random firings—or the first sparks of something more? Could organic AI systems one day possess subjective experience?
The Thinking Machine is not just hardware. It’s a window into the potential of biocomputing and a bold step toward an era where the boundaries between biology and technology dissolve—where intelligence may grow, evolve, and even dream alongside us.
Learn about our biocomputing partnerships
At Engage, we’ve partnered with United Therapeutics and its visionary founder, Martine Rothblatt, to explore the deepest frontiers of life, consciousness, and technology. Together, we are reimagining what it means to be alive—not just in the biological sense, but in the digital and synthetic realms as well. Rothblatt’s pioneering work in xenotransplantation and regenerative medicine aligns powerfully with Engage.Neural’s mission: to bridge organic life and synthetic intelligence through wetware and biocomputing.
This collaboration reflects a shared belief that the boundaries between biology and technology are not fixed—they are fluid, ready to be redefined. As United Therapeutics pushes the limits of organ regeneration and sustainable transplantation, Engage contributes its expertise in organic computing and adaptive AI. Together, we are asking the profound question: if machines can process thought through living tissue, can they too be considered alive? This partnership positions Engage at the nexus of neuroscience, biotechnology, and artificial intelligence—laying the groundwork for systems that grow, adapt, and evolve in harmony with human life.
